Publications Archive - Domain Therapeutics North America

Publications

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Find below reference publications demonstrating various applications of our biosensors, and the importance of GPCR signaling profiling

EGFR signaling and pharmacology in oncology revealed with innovative BRET-based biosensors

Chronic UCN2 treatment desensitizes CRHR2 and improves insulin sensitivity

A systematic analysis of prostaglandin E 2 type 3 receptor isoform signaling reveals isoform- a...

Common coupling map advances GPCR-G protein selectivity

Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of...

August 25, 2021

Mechanistic insights into dopaminergic and serotonergic neurotransmission – concerted interac...

September 9, 2019

Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to cli...

Biased Signaling of the Mu Opioid Receptor Revealed in Native Neurons

January 15, 2019

Crystal structure of misoprostol bound to the labor inducer prostaglandin E 2 receptor

September 16, 2016

A Pluridimensional View of Biased Agonism