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Find below reference publications demonstrating various applications of our biosensors, and the importance of GPCR signaling profiling
September 9, 2019
Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to cli...
April 26, 2019
Biased Signaling of the Mu Opioid Receptor Revealed in Native Neurons
January 15, 2019
Crystal structure of misoprostol bound to the labor inducer prostaglandin E 2 receptor
September 16, 2016
A Pluridimensional View of Biased Agonism
August 11, 2016
GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling
July 11, 2016
Monitoring G protein-coupled receptor and β-arrestin trafficking in live cells using enhanced ...
July 9, 2016
In Vitro Pharmacological Characterization of Buprenorphine, Samidorphan, and Combinations Being...
April 19, 2016
Mapping physiological G protein-coupled receptor signaling pathways reveals a role for receptor...
March 23, 2016
The conformational signature of β-arrestin2 predicts its trafficking and signalling functions
August 31, 2015
Receptor sequestration in response to β-arrestin-2 phosphorylation by ERK1/2 governs steady-st...